首页> 外国专利> CELL CULTURE SUBSTRATE, CELL CULTURING METHOD USING SUBSTRATE, AND METHOD FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING SUBSTRATE

CELL CULTURE SUBSTRATE, CELL CULTURING METHOD USING SUBSTRATE, AND METHOD FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING SUBSTRATE

机译:细胞培养基质,使用该基质的细胞培养方法以及使用该基质诱导多能干细胞分化的方法

摘要

The present invention has objectives of providing: a cell culture substrate which can culture pluripotent stem cells, and can differentiate the pluripotent stem cells into a specific cell, especially into a nerve cell in high purity; a cell culturing method using the same; and a method for inducing the differentiation of the pluripotent stem cells using the same. To solve the said objectives, the present invention provides the cell culture substrate which fixes or coats one or more kinds of fusion protein selected from the group consisting of: fusion protein including N-cadherin, or the entire or partial domains of the N-cadherin on the surface; and fusion protein including the entire or partial domains of protein having a homogeny with the N-cadherin.;COPYRIGHT KIPO 2014
机译:本发明的目的是提供:一种细胞培养基质,其可以培养多能干细胞,并且可以将多能干细胞分化成特定细胞,特别是高纯度地分化成神经细胞。使用该细胞培养方法的细胞;以及使用该方法诱导多能干细胞分化的方法。为了实现上述目的,本发明提供了一种细胞培养基质,其固定或包覆一种或多种选自以下的融合蛋白:包括N-钙粘蛋白的融合蛋白,或N-钙粘蛋白的全部或部分结构域。在表面上; COPYRIGHT KIPO 2014;以及融合蛋白,包括与N-cadherin具有同源性的蛋白的全部或部分结构域。

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