SELF-EXPANDABLE BIODEGRADABLE STENT MADE OF CLAD RADIOPAQUE FIBERS COVERED WITH BIODEGRADABLE ELASTIC FOIL AND THERAPEUTIC AGENT AND METHOD OF PREPARATION THEREOF

摘要

itself - as an expandable biodegradable stent, the core of the fiber is added to the polymer containing the X-ray opaque filler or coated with a polymer, or - Receive service X-ray impermeable material uniformly dispersed in the polymer fiber core, or - A polymer fiber core is coated with X-ray impermeable material is uniformly dispersed polymer, - Fibers that are twisted to form a complete primary structure of the stent may also be coated with a polymer dispersion and the X-ray opaque fillers, and the coating encapsulating the active material to form a biodegradable foil provided on the basic structure of the stent, the The active material is selected from the group of materials including medicaments, proteins, enzymes, genes, stem cell or a radioactive material used in the topical treatment of tumors. Self-expansible A method of manufacturing a biodegradable stent, the method comprising coating a core containing a polymer fiber with the addition of X-ray opaque filler polymer, or - A step in which the core polymer fiber X-ray impermeable material is uniformly dispersed, or - A step of coating a polymer core fibers in the x-ray impermeable material is uniformly dispersed polymer, - And then coating the twisted fiber to form a complete primary structure of the stent and the polymer dispersion in the X-ray opaque fillers to provide a biodegradable foil the basic structure of the stent, the active substance is encapsulated in the foil, in a step X-ray opaque filler undergoes a heat treatment is provided with the stent, and then coated with a biodegradable elastic foil made of a X-ray opaque fibers containing a first medicament, and in this way is manufactured, the stent undergoes a second heat treatment , and a different addition of a thinner foil as a step in a biodegradable coating again comprising a second medicament. ;