首页> 外国专利> USE OF PPAR AGONISTS AS ANTIBIOTICS, THERAPEUTICS FOR TREATMENT OF BURNS, WOUNDS AND DIABETIC ULCERS

USE OF PPAR AGONISTS AS ANTIBIOTICS, THERAPEUTICS FOR TREATMENT OF BURNS, WOUNDS AND DIABETIC ULCERS

机译:使用PPAR激动剂作为抗生素,治疗烧伤,伤口和糖尿病溃疡的药物

摘要

The present invention relates to a novel use of a PPAR agonist and, particularly, to antibacterial activities, diabetic foot ulcer treatment and prevention ettects, and gash and burn treatment effects of a PPAR agonist. According to the present invention, the PPAR agonist has excellent antibacterial activities against methicillin- and vancomycin-resistant bacteria and can be used as an agent for preventing or treating multidrug resistance bacterial infection. The PPAR agonist has excellent wound treating efficiency through the cell movement and proliferation of epidermal keratinocytes and has excellent ulcer treating efficiency in a diabetic ulcer animal model, so as to effectively treat gash, burn, and foot ulcer caused by diabetic complications.
机译:本发明涉及PPAR激动剂的新用途,特别是涉及PPAR激动剂的抗菌活性,糖尿病性足溃疡的治疗和预防性gas病,以及烧伤和烧伤的治疗作用。根据本发明,PPAR激动剂对耐甲氧西林和万古霉素的细菌具有优异的抗菌活性,并且可以用作预防或治疗耐多药细菌感染的试剂。 PPAR激动剂通过细胞移动和表皮角质形成细胞的增殖而具有优异的伤口处理效率,并且在糖尿病性溃疡动物模型中具有优异的溃疡处理效率,从而有效地治疗由糖尿病并发症引起的烧伤,烧伤和足溃疡。

著录项

  • 公开/公告号KR20140082451A

    专利类型

  • 公开/公告日2014-07-02

    原文格式PDF

  • 申请/专利权人 SNU R&DB FOUNDATION;

    申请/专利号KR20120152442

  • 申请日2012-12-24

  • 分类号A61K31/426;A61K31/435;A61P17/02;A61P17;

  • 国家 KR

  • 入库时间 2022-08-21 15:42:35

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