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USE OF PPAR AGONISTS AS ANTIBIOTICS, THERAPEUTICS FOR TREATMENT OF BURNS, WOUNDS AND DIABETIC ULCERS
USE OF PPAR AGONISTS AS ANTIBIOTICS, THERAPEUTICS FOR TREATMENT OF BURNS, WOUNDS AND DIABETIC ULCERS
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机译:使用PPAR激动剂作为抗生素,治疗烧伤,伤口和糖尿病溃疡的药物
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摘要
The present invention relates to a novel use of a PPAR agonist and, particularly, to antibacterial activities, diabetic foot ulcer treatment and prevention ettects, and gash and burn treatment effects of a PPAR agonist. According to the present invention, the PPAR agonist has excellent antibacterial activities against methicillin- and vancomycin-resistant bacteria and can be used as an agent for preventing or treating multidrug resistance bacterial infection. The PPAR agonist has excellent wound treating efficiency through the cell movement and proliferation of epidermal keratinocytes and has excellent ulcer treating efficiency in a diabetic ulcer animal model, so as to effectively treat gash, burn, and foot ulcer caused by diabetic complications.
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