NOVEL ANTIMICROBIAL PEPTIDE DERIVED FROM RIBOSOMAL PROTEIN L1 OF HELICOBACTER PYLORI AND USE THEREOF

摘要

The present invention relates to a novel antibiotic peptide derived from ribosomal protein L1 of Helicobacter pylori and a use thereof. Specifically, a novel peptide of SEQ ID NO: 4 was synthesized by substituting proline for phenylalanine, which is the 12th amino acid of a peptide consisting of an amino acid sequence of SEQ ID NO: 3. The novel peptide was confirmed to exhibit significant antibiotic activity and have no cytotoxicity, and thus the novel peptide can be used as an active ingredient of a natural antibiotic agent.