PREPARATION METHOD OF HIGHLY PURE PEMETREXED DISODIUM SALT

摘要

The present invention provides a preparation method of pemetrexed disodium salt. The present invention can prepare the pemetrexed disodium salt with at least 99.9% purity and preferably with 99.95% or more ultra-purity. Thus, the pemetrexed disodium salt can be sued as an active ingredient without an additional purification process.