Novel Tetranuclear Arene-Ruthenium Compound and Parmaceutical Composition for Preventing or Treating Cancer Containing Thereof

摘要

The present invention relates to novel quaternary arene-ruthenium compounds or pharmaceutically acceptable salts thereof, which include human SK-hep-1 (liver cancer), HeLa (ovarian cancer), HCT-15 (rectal cancer), A549 (lung cancer) ), And inhibits the proliferation of MDA-MB-231 (breast cancer) cells at low micromolar concentrations and inhibits the activity of cancer cells through apoptosis that regulates cell growth cycle. It can be usefully used for the prevention and treatment of cancers such as cancer, rectal cancer, lung cancer, breast cancer.