RADIOISOTOPE LABELLED FOLIC ACID CONJUGATE COMPOUND SPECIFIC TO CANCER AND SENTINEL LYMPH NODE

摘要

The invention includes a specific radioisotope an element labeled folate binding of serum albumin and its manufacturing method, folate binding thiol of the added mixture of methylene Depot spokes acid, ascorbic acid and stannous chloride to the serum albumin to the tumor, and lymphoid tissues which relates to a tumor and the sentinel lymph node image one-time-use kit and preparation method thereof, and a radioactive isotope and imaging a tumor cell image composition method for Localization transition in sentinel nodes containing an element-labeled folate binding of serum albumin. According to the invention, to reduce the possibility of false negative, useful to provide a lingers passive markers characteristic and specific active markers characteristic to bring SLN SLN markers accuracy has been increased in the biopsy at the same time to bind to the tumor with the lymph nodes effect have. ;