Chlorin derivatives and unsaturated fatty acids conjugate, a photosensitizer comprising the same, and a composition for treatment of cancer for using in photodynamic therapy comprising the same

摘要

The present invention relates to chlorine derivative/unsaturated fatty acid conjugates, to photosensitizers comprising same, and to cancer treatment compositions to be used in photodynamic therapy comprising the same. The present invention relates to chlorine derivative/unsaturated fatty acid conjugates in which chlorine derivatives are combined with unsaturated fatty acids such as docosahexaenoic acid (DHA) or oleic acid (OA) to achieve improved tumor selectivity and reduced cytotoxicity. Thus, the conjugates of the present invention can be used effectively in photodynamic therapy for cancer.