首页> 外国专利> A Label-free Bio-sensor Using the Change of Liquid Crystal Arrays and Imaging

A Label-free Bio-sensor Using the Change of Liquid Crystal Arrays and Imaging

机译:使用液晶阵列和成像技术的无标签生物传感器

摘要

The present invention comprises (a) a substrate (substrate); And (b) a functional (functional) compound-comprising doped (doped) LCD (liquid crystal) of the functional compound is chemically modified by the enzyme and the functional compound or metabolite (metabolite) of the detection target microorganism wherein the liquid crystal orientation is by chemical modification of (orientation) is changed and optical appearance (optical appearance) characterized in that the liquid crystal is changed microorganism detection-based relates to a biosensor. The biosensor of the present invention may be functional (functional) compound is visually observed in real-time the presence or absence of a particular microorganism or enzyme in a sample by using a doped (doped) crystal. According to the present invention, can be observed with high sensitivity and high directivity (orientational) at the interface with the optical change due to the reaction occurring chemical / biochemical reaction of only the image of the liquid crystal to know quickly and easily detected in a sample or not. ;
机译:本发明包括(a)衬底(substrate);并且(b)通过酶和检测目标微生物的功能化合物或代谢产物(代谢产物)对所述功能化合物的包含功能(功能)化合物的掺杂(掺杂)LCD(液晶)进行化学修饰,其中液晶取向通过化学修饰(取向)而改变的光学外观(光学外观)的特征在于,液晶改变是基于微生物检测的,涉及生物传感器。本发明的生物传感器可以是功能性(功能性)化合物,通过使用掺杂(掺杂)的晶体实时地目视观察样品中是否存在特定微生物或酶。根据本发明,可以以高灵敏度和高方向性(方向性)在与光学变化的界面处观察到,所述光学变化是由于反应发生的,仅液晶图像的化学/生化反应就可以快速,容易地检测到。是否采样。 ;

著录项

  • 公开/公告号KR101407545B1

    专利类型

  • 公开/公告日2014-06-12

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120050361

  • 发明设计人 장창현;

    申请日2012-05-11

  • 分类号G01N33/569;C12Q1/04;G01N33/573;

  • 国家 KR

  • 入库时间 2022-08-21 15:40:45

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