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A METHOD OF PREPARING LYSOSOME HAVING ANTIBACTERIAL ACTIVITY AND ANTI-CANCER ACTIVITY

机译:具有抗微生物活性和抗癌活性的溶酶体的制备方法

摘要

The present invention relates to a method for preparing lysosome with antibacterial and anticancer activities; an antibacterial composition containing the lysosome prepared by the method; as an active ingredient; and an anticancer composition containing the lysosome prepared by the method as an active ingredient. More particularly, the method for preparing the lysosome with antibacterial and anticancer activities comprises the steps of: introducing N-terminal peptide hydrolase gene and a regulatory gene into a eukaryote and preparing a mutant; culturing the mutant in which N-terminal peptide hydrolase and the regulatory gene are introduced; and obtaining lysosome from the cultured mutant. The lysosome is identified to have remarkably improved anticancer and anti-bacterial activities.
机译:本发明涉及一种具有抗菌和抗癌活性的溶酶体的制备方法。包含通过该方法制备的溶酶体的抗菌组合物;作为有效成分;含有通过该方法制备的溶酶体作为有效成分的抗癌组合物。更特别地,具有抗菌和抗癌活性的溶酶体的制备方法包括以下步骤:将N-末端肽水解酶基因和调节基因引入真核生物中,并制备突变体。培养导入了N末端肽水解酶和调控基因的突变体。从培养的突变体中获得溶酶体。溶酶体被鉴定具有显着改善的抗癌和抗菌活性。

著录项

  • 公开/公告号KR101421534B1

    专利类型

  • 公开/公告日2014-07-24

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120047763

  • 发明设计人 윤지희;민지호;김양훈;

    申请日2012-05-04

  • 分类号A61K48;A61K38/46;A61K38/43;A61P35;

  • 国家 KR

  • 入库时间 2022-08-21 15:40:26

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