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PIPERIDINYL PYRIMIDINE AMIDES AS KV7 POTASSIUM CHANNEL OPENERS

机译:哌啶嘧啶酰胺作为KV7钾离子通道开放剂

摘要

The present invention relates to compounds of Formula (I) as described herein or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof and methods of treating, or manufacture of a medicament to treat, a disease, disorder, or condition of the central nervous system, including bipolar disorder, depressive disorders, anxiety disorders, cognitive disorders, pain disorders, urogentital disorder, and epilepsy, among the other diseases, disorders or conditions discussed herein as mono-therapy or in combination with another active pharmaceutical ingredient.
机译:本发明涉及本文所述的式(I)的化合物或其药学上可接受的盐,包含式(I)的化合物或其药学上可接受的盐的药物组合物以及治疗或制备用于治疗,中枢神经系统的疾病,病症或病状,包括双相情感障碍,抑郁症,焦虑症,认知障碍,疼痛症,泌尿生殖系统病和癫痫病,以及本文中作为单一疗法讨论的其他疾病,病症或病状与另一种活性药物成分结合使用。

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