COMBINED PHARMACEUTICAL COMPOSITION FOR TREATMENT arterial hypertension congestive heart failure and chronic heart failure

摘要

1. A pharmaceutical composition for treating cardiovascular diseases in a solid dosage form which comprises ramipril in a therapeutically effective amount of the combined stabilizer, filler, binder, disintegrant and lubricant, characterized in that it further comprises indapamid.2. A pharmaceutical composition according to claim 1, characterized in that it contains as stabilizer a combination of sodium hydrogen carbonate and the colloidal silicon dioxide gidrofobnogo.3. A pharmaceutical composition according to claim 2, characterized in that it comprises additionally krasitel.4. A pharmaceutical composition according to claim 3, characterized in that it comprises as a colorant Iron oxide yellow or iron oxide krasnyy5. A pharmaceutical composition according to claim 3, characterized in that it comprises ramipril, indapamide, sodium hydrogencarbonate and hydrophobic colloidal silica in the following proportion, mass.ch.Ramipril - 1,0Indapamid - sodium 0,24-0,37Gidrokarbonat - 0.04- 0,72Dioksid hydrophobic colloidal silica - 0,08-1,66. A pharmaceutical composition according to claim 5, characterized in that it comprises as filler the combination of lactose monohydrate and microcrystalline cellulose as the binder hypromellose as sodium croscarmellose disintegrant, and as a lubricant and a glidant comprises lubrikant.7. A pharmaceutical composition according to claim 6, characterized in that it is made in the form of a tablet.