VACCINE AGAINST associated virus diarrhea, rotavirus and coronavirus infections in cattle emulsion INACTIVATED

摘要

1. A vaccine against a viral-associated diarrhea (VD), rotavirus and coronavirus infections of cattle (RNC) inactivated emulsion containing the active substance and the desired additives, characterized in that as an active substance it contains a mixture of purified antigenic material avirulent strain " NADL-ARRIAH "virus WA cattle, herewith. Flaviviridae, genus Pestivirus, collection FSI "VGNKI» «NADL-ARRIAH" -DEP from avirulent antigenic material purified from strain «№101 ARRIAH" rotavirus RNC, Sem. Reoviridae, genus Rotavirus, collection VGNKI «№101 ARRIAH-DEP" and purified from the avirulent antigenic material from strain "ARRIAH" RNC coronavirus, Sem. Coronaviridae, kind Coronaivirus, collection VGNKI "ARRIAH-DEP" in an effective kolichestve.2. Vaccine according to claim 1, characterized in that it contains an avirulent and purified antigenic material from strain «NADL-ARRIAH" VD RNC virus obtained in continuous culture of mammalian cells in an effective kolichestve.3. Vaccine according to claim 2, characterized in that it contains an avirulent and purified antigenic material from strain «NADL-ARRIAH" VD RNC virus obtained in continuous culture of bovine kidney cells (Taurus-2) in the effective kolichestve.4. A vaccine according to claim 3, characterized in that it contains an avirulent and purified antigenic material from strain «NADL-ARRIAH" RNC virus obtained in the continuous culture of cells Taurus-2 infectivity least 6,0 lg TCD / cc activity in ELISA not less than 6.65 1ogdo inactivation in an amount of 10.0 wt.%. 5. Vaccine according to claim 2, characterized in that it contains an avirulent and purified antigenic material from strain «NADL-ARRIAH" virus VD RNC resultant ne