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METHOD FOR PREPARING SOLID DOSAGE FORM, PARTICULARLY TABLET FOR PHARMACEUTICAL APPLICATION AND METHOD FOR PREPARING SOLID DOSAGE FORM PRECURSOR, PARTICULARLY TABLET

机译:制备固体剂型特别是药片的片剂的方法和制备固体剂型特别是片剂的片剂的方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to chemical-pharmaceutical industry, particularly to a method for preparing a powder. The method involves the stages of providing at least one first ingredient that has a consistence of viscous fluid and that has an initial melting point within the temperature range of 15°C to 40°C, providing at least one second ingredient that has a melting point, particularly within the range above an ambient temperature up to 120°C, preparing a homogenous liquid mixture containing one first ingredient and one second ingredient by mixing and heating the mixture to a temperature or maintaining a temperature of the mixture within the range above the melting point. Supplying the liquid mixture to an irrigation hardening unit and extracting the powder prepared by irrigation hardening. In addition, the present invention refers to the method for preparing the solid dosage form containing the powder prepared by the method described above.;EFFECT: improvement of the method.;17 cl, 6 ex, 2 tbl
机译:粉末的制备方法技术领域:本发明涉及化学药物工业,尤其涉及一种粉末的制备方法。该方法包括以下步骤:提供至少一种第一成分,该第一成分具有粘性流体并且具有在15℃至40℃的温度范围内的初始熔点;提供至少一种第二成分,该第二成分具有熔点。尤其是在高于环境温度至多120°C的温度范围内,通过混合并将混合物加热至一定温度或将混合物的温度保持在熔融温度以上的范围内,制备含有一种第一成分和一种第二成分的均质液体混合物点。将液体混合物供应至冲洗硬化单元并提取通过冲洗硬化制备的粉末。另外,本发明涉及制备包含通过上述方法制备的粉末的固体剂型的方法。效果:方法的改进; 17 cl,6 ex,2 tbl

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