1-(2-ARYLOXYETHYL)- AND 1-BENZYL-SUBSTITUTED 3-(2-HYDROXYETHYL)-2-IMINOBENZIMIDAZOLINE DERIVATIVES, HAVING ANTIBACTERIAL AND ANTI-PROTIST ACTIVITY

摘要

FIELD: chemistry.;SUBSTANCE: present invention relates to an agent, having antibacterial and anti-protist activity, based on a hydrochloride of formula (1a-k) , where R=C₆H₅OCH₂ (a); 4-CH₃C₆H₄OCH₂ (b); 4-OCH₃C₆H₄OCH₂ (c); 2-OCH₃C₆H₄OCH₂ (d); 4-FC₆H₄OCH₂ (e); 2-ClC₆H₄OCH₂ (f); C₁₀H₇OCH₂ (g); 2,4-Cl₂C₆H₃OCH₂ (h); 4-BrC₆H₄OCH₂ (i); 2-FC₆H₄ (j); 2-ClC₆H₄ (k).;EFFECT: obtaining a novel agent, having antibacterial and anti-protist activity, particularly with respect to Staphylococcus aureus and Escherichia coli bacteria, and moderate anti-protist activity with respect to elementary Colpoda steinii.;1 tbl