PHARMACEUTICAL SALT OF 8-METHYL-7-5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-3-QUINOLINE CARBOXYLIC ACID, PHARMACEUTICAL COMPOSITION CONTAINING SAME, MEDICINAL AGENT AND METHOD OF TREATING OR PREVENTING BACTERIAL INFECTIONS USING SAID SALTS

摘要

FIELD: chemistry.;SUBSTANCE: present invention relates to a pharmaceutical salt of 8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-1-cyclopropyl-4-oxo-1,4-dihydro-3-quinoline carboxylic acid, characterised by that it is in form of a hydrochloride monohydrate and by solubility of at least 0.050 mg/ml water. The invention also relates to a pharmaceutical composition based on said pharmaceutical salt, use of said pharmaceutical salt and a method of treating or preventing bacterial infections based on use of said pharmaceutical salt.;EFFECT: obtaining a novel pharmaceutical salt of 8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-1-cyclopropyl-4-oxo-1,4-dihydro-3-quinoline carboxylic acid, characterised by good solubility in water, which influences bioavailability of the active ingredient.;7 cl, 16 dwg, 2 tbl, 9 ex