PHARMACEUTICAL COMPOSITION OF LIGANDS OF RECEPTORS OF SECRETAGOGUES OF GROWTH HORMONE

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to a pharmaceutical composition of clear solution containing peptide, where the said peptide is H-Inp-D-Bal-D-Trp-Phe-Apc-NH2, acting as a ligand of receptor GHS, or its pharmaceutically acceptable salt. This peptide forms a depot in situ after subcutaneous or intramuscular injection to a subject. The pharmaceutical composition additionally comprises PEG, the said peptide is in the form of the pamoate salt, and the clear solution is an aqueous solution.;EFFECT: significant increase of the hormone as compared to the preparation of the acetate salt.;13 cl, 1 ex, 2 dwg, 5 tbl