The use of a test apparatus and method for the assay of cells, cell cultures and / or organotypical cell assemblages

摘要

The use of a test device for cells, cell cultures and / or an organotypic cell assemblages (51), wherein said test devicean array (52) of microelectrodes (53) on which the cells, cell cultures and / or an organotypic cell assemblages (51) are cultured,an array (54) of radiation emitting elements (55), which the cells, cell cultures and / or organotypical cell assemblages (51) in a spatially resolved manner, with electromagnetic radiation within and / or outside of the visible spectrum, illuminate,an actuation device (56), in order to the array (54) of radiation emitting elements (55) for the emission of electromagnetic radiation, and to trigger spatially resolvedan evaluation unit (58), in order to determine and evaluate the signals from the cells, cell cultures and / or organotypical cell unions (51) in the case of illumination by the array (54) of radiation emitting elements (55) to the microelectrodes (53) are emitted,characterised in that said cells, cell cultures and / or an organotypic cell assemblages (51, which can be tested were equipped with light-sensitive channels, for example, by means of transfection with, if appropriate, viral vectors for the expression of, for example. channelrhodopsin-2.