Method for determining the susceptibility getting an infection in nosocomial in a patient presenting a systemic inflammatory response associated or not have an infection.

摘要

Determining susceptibility for contracting nosocomial infection in a patient having a systemic inflammatory response (non)associated with an infection, comprises collecting a biological sample from the patient and extracting biological material from biological sample; taking at least one specific reagent from an expression product of the target gene S100A9; and determining the expression of the target gene S100A9. Independent claims are included for: (1) establishing an early prognosis of survival in a patient having a systemic inflammatory response (non)associated with infection, or for determining the etiology of a systemic inflammatory response (non)associated with infection in patient, comprising (a) collecting biological sample from the patient and extracting from biological material from the biological sample, (b) collecting at least one reagent specific for an expression product of the target gene S100A9 and (c) determining the expression of the S100A9 target gene; (2) a first kit for determining susceptibility in contracting nosocomial infection in a patient having a systemic inflammatory response (non)associated with an infection comprising one reagent specific for S100A9 gene expression product; (3) use of at least one reagent for determining, in vitro, the susceptibility for contracting a nosocomial infection in a patient having systemic inflammatory response (non)associated with an infection; (4) a second kit for establishing an early prognosis for survival in a patient having a systemic inflammatory response (non)associated with an infection comprising at least one reagent specific for an expression product of S100A9 gene; and (5) use of at least one reagent for establishing, in vitro, a prognosis for survival in a patient having a systemic inflammatory response (non)associated with an infection.