EVALUATION METHOD AND INDEX MATERIAL OF PREPARATION CONTAINING LULICONAZOLE

摘要

PROBLEM TO BE SOLVED: To provide an evaluation method of stability for a preparation containing luliconazole and the preparation excellent in stability.;SOLUTION: An evaluation method of stability for a preparation containing luliconazole measures a generation amount of the SE form of the luliconazole, a generation amount of the Z form of the luliconazole, and a generation amount of the amido form of the luliconazole represented by the following formula (1) when being stored under a severe condition or an acceleration condition. When the generation amount of the SE form, the generation amount of the Z form, and the generation amount of the amido form are respectively 5 mass% or less of the blending amount of the luliconazole, the preparation is determined to have the high stability. And a preparation conforming to the evaluation method is provided.;COPYRIGHT: (C)2015,JPO&INPIT