System and method for automatic determination of relative effectiveness of anticancer drug candidates

摘要

A computer system is provided for determining the relative effectiveness of anticancer agents. The interface has selectable options including options for managing drug test parameters and allows user selection of desired drug test parameters associated with a virtual well plate associated with a spectrophotometer physical well plate To do. The computer system causes the spectrophotometer to initiate a drug test, where the physical well plate includes at least one test well containing live cancer cells and a predetermined concentration of at least one drug candidate, and only live cancer cells. And at least one control well. The system records the optical density of the well at a given wavelength over a selected time interval at a selected time interval and stores the optical density and time measurements in a database. An activity value is calculated from the optical density and time measurements and a correlation between the activity value and the drug candidate's ability to induce apoptosis in cancer cells is displayed. [Selection] Figure 7