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Compounds and methods for reducing mobilization and / or migration of polymorphonuclear cells

机译:减少多形核细胞动员和/或迁移的化合物和方法

摘要

A therapeutically effective amount of an oligonucleotide is capable of influencing the properties and behaviour of polymorphonuclear cells, e.g. suppressing endothelial adhesion and transmigration of said cells, and through this mechanism reduce the recruitment and/or migration of polymorphonuclear cells to a site of inflammation.
机译:治疗有效量的寡核苷酸能够影响多形核细胞的特性和行为,例如多形核细胞。抑制内皮粘附和所述细胞的迁移,并通过这种机制减少多形核细胞向炎症部位的募集和/或迁移。

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