Human skin sampling methods and models for evaluating the color tone specific effect of the drug

摘要

Human skin tissue sampling methods and models for identifying and screening test drugs as effective in providing skin tone effects, methods for verifying hypotheses about mechanisms driving skin pigmentation, and ex vivo skin tissue A method for driving skin pigment levels in the skin. This method is effective in providing a skin tone effect by contacting a cultured human skin tissue sample with a test agent, generating a transcription profile from the sample, and comparing the results to a control. Determining whether or not.