Superparamagnetic nanoparticles as contrast agent (T2 *) in magnetic resonance imaging (MRI) of magnetic sensitivity (MAGNETICSUSCEPTIBILITY)

摘要

The present invention relates to the use of biocompatible superparamagnetic nanoparticles comprising an inorganic core and a charged polymer coating, having low tissue adhesion and low vascular adhesion and as a contrast agent in magnetic resonance imaging (MRI). About the use of. The nanoparticles have novel pharmacokinetic and T2 * relaxation properties and have high potential for use in in vivo tissue imaging and tumor perfusion strategies based on T2 * parameters. [Selection figure] None