pharmacologically active substance excavation method of the high-resolution mass spectrometry and pharmacological activity test natural products using the

摘要

To discover fast pharmacologically active components contained in a plurality of samples, the step of creating an activity profile by examining the pharmacological activity of multiple samples, the present invention is analyzed by mass spectrometry the sample the basis of the mass spectrum obtained Te, and comparing the mass profile of the activity profile and steps to create a mass profile, analyze, pharmacologically active substance of natural products, including the step of determining the molecular weight of a pharmacologically active substance I provide the excavation method. By using high resolution mass spectrometer, and compared with the activity test material at the same time as determined from the high resolution mass spectrum molecular formulas configuration numerous compounds contained in natural product extract sample, the present invention, the pharmacologically active fast can be excavated materials, efficient use of natural products is possible with the information about the strength of activity by activity data of the pharmacologically active substances of natural products that have been collected at this time. [Selection Figure Figure 5