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Subconjunctival fibroblast growth inhibitors and subconjunctival fibroblast growth suppression method

机译:结膜下成纤维细胞生长抑制剂和结膜下成纤维细胞生长抑制方法

摘要

PROBLEM TO BE SOLVED: To provide an inhibitor of subconjunctival fibroblast proliferation, capable of safely and efficiently inhibiting conjunctival synechia and the formation of subconjunctival cicatricial tissue after an ophthalmic operation.;SOLUTION: The inhibitor is an inhibitor of subconjunctival fibroblast proliferation using trehalose, and it is also used as an inhibitor of conjunctival synechia or an inhibitor of subconjunctival cicatricial tissue formation especially in the form of eye-drops. In the presence of trehalose at a concentration of not lower than 5%, it can restrain the proliferation of fibroblast more as the concentration is higher, meanwhile, it has utterly no effect on the proliferation of epidermal cells.;COPYRIGHT: (C)2011,JPO&INPIT
机译:解决的问题:提供一种结膜下成纤维细胞增殖的抑制剂,能够安全有效地抑制眼科手术后的结膜粘连和结膜下结缔组织的形成;解决方案:该抑制剂是使用海藻糖抑制结膜下成纤维细胞增殖的抑制剂。它也用作结膜粘连的抑制剂或结膜下瘢痕组织形成的抑制剂,尤其是以滴眼剂的形式。在浓度不低于5%的海藻糖存在下,其浓度越高,它对成纤维细胞增殖的抑制作用就越大,而对表皮细胞的增殖完全没有影响。;版权所有:(C)2011 ,JPO&INPIT

著录项

  • 公开/公告号JP5685751B2

    专利类型

  • 公开/公告日2015-03-18

    原文格式PDF

  • 申请/专利权人 国立大学法人弘前大学;

    申请/专利号JP20090181976

  • 发明设计人 蝦名 祐一;竹内 侯雄;中澤 満;

    申请日2009-08-04

  • 分类号A61K31/7016;A61P27/02;A61P43/00;C07H3/04;A61P27/06;

  • 国家 JP

  • 入库时间 2022-08-21 15:30:44

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