for a damaged or manufacture of endothelial / epithelial regeneration medicament for tissue or organs injured, method of use, as well as relevant in vitro and in vivo stem cell-derived microvesicles (MV)

摘要

PROBLEM TO BE SOLVED: To provide a use of a medicament which inhibits apoptosis induced by the use of inhibitors for cell growth in chemotherapy such as an anticancer drug, paclitaxel, and is suitable for regeneration of tissue, especially endothelial/epithelial regeneration.SOLUTION: A method for the use of a medicament for inhibiting apoptosis by a stem cell derived microvesicles is provided. The stem cell from which microvesicles are originated is preferably selected from the group consisting of endothelial progenitor cells (EPCs), mesenchymal stem cells (MSCs), renal progenitor cells CD133+, adult liver stem cells (HLSC) and any combination thereof.