Sirtuin inducer, tissue repair agent, hepatocyte growth factor inducer, tissue homeostasis maintainer, and TLR4 agonist containing hyaluronic acid fragment as an active ingredient

摘要

A sirtuin inducer, tissue repair agent, hepatocyte growth factor inducer, tissue homeostasis maintainer, or TLR4 agonist using a hyaluronic acid fragment is provided. A hyaluronic acid fragment selected from sizes of 2 to 20 sugars, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, and a sirtuin inducer, tissue repair agent, hepatocyte growth factor induction It is used as an active ingredient of an agent, tissue homeostasis, or TLR4 agonist. The hyaluronic acid fragment is preferably a hyaluronic acid fragment selected from a size of 3 to 10 sugars, more preferably a trisaccharide or tetrasaccharide hyaluronic acid fragment.