A lipidomic biomarker for predicting cardiovascular outcome in patients with coronary artery disease receiving statin therapy

摘要

In particular, the present invention provides methods and uses thereof for predicting severe CVD complications such as AMI or CVD death by detecting lipid concentration or ratio of lipid in a biological sample and comparing it to a control. We identified specific lipid markers that are more specific and sensitive than clinical markers currently used in predicting CVD complications. Also provided are antibodies directed to said lipids and their use for predicting, diagnosing, preventing and / or treating CVD complications. The invention further relates to kits comprising lipids and / or antibodies thereto for use in the prediction and / or diagnosis of CVD complications.