causal factor detection method and male infertility animal model of male infertility

摘要

GALNTL5 gene mutations or to detect the male infertility to index the abnormal expression of GALNTL5 protein to provide a method, and Galntl5 gene to provide a mutation has been introduced human male infertility model animal. To detect the male subjects male infertility to index the abnormal expression of GALNTL5 genes in sperm, the detection method of male infertility, and all or part of the sperm of the gene is missing, or GALNTL5 protein expression is lost, or decline to have, male infertility non-human animal model.