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DIAGNOSTIC AND PROGNOSTIC ASSAYS BASED ON CIRCULATING TYROSNE KINASE ACTIVITY
DIAGNOSTIC AND PROGNOSTIC ASSAYS BASED ON CIRCULATING TYROSNE KINASE ACTIVITY
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机译:基于循环酪氨酸激酶活性的诊断和预后分析
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摘要
Provided herein are methods for the diagnosis, prognosis, or management of diseases, such as cancer, by measuring the tyrosine kinase activity in acellular body fluids. Further provided are methods of predicting response to therapy in certain populations of cancer patients by contacting an acellular body fluid sample from a patient with a test agent, such as a tyrosine kinase inhibitor, and then measuring the effect of the test agent on tyrosine kinase activity in the sample.
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