embedded image ;or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein."/> Methods of Using Diaminopyrimidine P2X3 and P2X 2/3 Receptor Modulators for Treatment of Acute and Sub-Acute Cough, Urge to Cough and Chronic Cough, in Respiratory Diseases
首页> 外国专利> Methods of Using Diaminopyrimidine P2X3 and P2X 2/3 Receptor Modulators for Treatment of Acute and Sub-Acute Cough, Urge to Cough and Chronic Cough, in Respiratory Diseases

Methods of Using Diaminopyrimidine P2X3 and P2X 2/3 Receptor Modulators for Treatment of Acute and Sub-Acute Cough, Urge to Cough and Chronic Cough, in Respiratory Diseases

机译:使用二氨基嘧啶P2X3和P2X 2/3受体调节剂治疗呼吸系统疾病的急性和亚急性咳嗽,促咳嗽和慢性咳嗽的方法

摘要

Methods for treating cough, chronic cough and urges to cough associated with respiratory diseases with a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of Formula (I):; embedded image ;or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein.
机译:用P2X3和/或P2X2 / 3受体拮抗剂治疗与呼吸系统疾病相关的咳嗽,慢性咳嗽和急咳的方法,该方法包括向有需要的受试者施用有效量的式(I)的化合物: ; “嵌入式图像” ;或其药学上可接受的盐,其中R 1 和R 2 如本文所定义。

著录项

  • 公开/公告号US2015057299A1

    专利类型

  • 公开/公告日2015-02-26

    原文格式PDF

  • 申请/专利权人 AFFERENT PHARMACEUTICALS INC.;

    申请/专利号US201414466713

  • 发明设计人 ANTHONY P. FORD;BRUCE G. MCCARTHY;

    申请日2014-08-22

  • 分类号C07D239/48;

  • 国家 US

  • 入库时间 2022-08-21 15:22:28

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