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Prediction of horizontally transferred gene

机译:水平转移基因的预测

摘要

Method(s) and system(s) for identifying horizontally transferred genes are described herein. The method includes defining a cuboid in a three dimensional space, wherein the cuboid includes fragment points corresponding to the genomic fragments belonging to a plurality of sequenced microbial genomes, and dividing the cuboid into a plurality of grids. The method further includes selecting one or more grids corresponding to a selected genome and classifying each of the selected grids as one of majority, minority, and mixed grids, based on number of fragment points corresponding to the selected genome in each of the selected grids. Further, at least one genomic fragment from the minority and the mixed grids is identified as the horizontally transferred gene based on a distance ratio assessment.
机译:本文描述了用于鉴定水平转移的基因的方法和系统。该方法包括在三维空间中定义一个长方体,其中该长方体包括与属于多个测序的微生物基因组的基因组片段相对应的片段点,并且将该长方体划分为多个网格。该方法还包括基于对应于每个选定网格中的选定基因组的片段点的数量,选择与选定基因组相对应的一个或多个网格,并将每个选定网格分类为多数,少数和混合网格之一。此外,基于距离比评估,将来自少数族群和混合网格的至少一个基因组片段鉴定为水平转移的基因。

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