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Screening assays for compounds that modulate programmed ribosomal frameshifting
Screening assays for compounds that modulate programmed ribosomal frameshifting
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机译:筛选可调节程序化核糖体移码的化合物的检测方法
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摘要
The present invention relates to compounds that modulate ribosomal frameshifting and nucleic acid constructs for use in methods for identifying or validation of compounds that modulate ribosomal frameshifting. In particular, the present invention relates to the use of nucleic acid constructs to identify or validate compounds capable of modulating the efficiency of programmed ribosomal frameshifting and the use of compounds that modulate the efficiency of programmed ribosomal frameshifting to inhibit the replication or infectivity of viruses that employ programmed ribosomal frameshifting.
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