A computer-aided method (30) comprises alternating between one or more of (i) navigational tasks and (ii) measuring, qualification, and quantification tasks of a clinical task in accordance with defined simple click style user interactions. The defined simple click style user interactions are based upon a domain knowledge (34) that includes (i) details of an anatomy and (ii) details of a clinical measurement, quantification, or workflow of the clinical task associated with the anatomy. Responsive to execution of a simple click style user interaction within a current view (36), and further in accordance with a corresponding navigational task or measuring, qualification, or quantification task, the method transitions within the clinical task and its workflow between one or more of (a) a first measurement point and a next measurement point within the current view (36) or (b) the current view (36) and a next view (38).
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