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High throughput and volumetric error resilient dilution with digital microfluidic based lab-on-a-chip
High throughput and volumetric error resilient dilution with digital microfluidic based lab-on-a-chip
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机译:基于数字微流控芯片实验室的高通量和体积误差弹性稀释
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摘要
Systems and methods are provided for producing fluids with desired concentration factors from the given supply of any two concentration factors, one greater than the target CF and one less than the target CF, of the same fluid. According to one embodiment, a method is provided that stores intermediate waste droplets from a sequence of mix and split steps and repeats certain steps of the sequence using the stored intermediate waste droplets. Such a method may produce additional target CF droplets faster than repeating the entire sequence. In another embodiment, a method of volumetric error resilient target CF droplet generation has been described, and includes reusing the stored intermediate waste droplets and involves a collection of capacitive sensing circuits associated with some electrode platforms.
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