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Vectorization of dsRNA by cationic particles and use of same on a skin model

机译:阳离子粒子对dsRNA的矢量化及其在皮肤模型中的使用

摘要

The present invention relates to vectorization of double stranded RNA oligonucleotides by cationic particles chosen from among surfactant micelles, block or non-block polymer micelles, cationic liposomes and niosomes, cationic oleosomes and cationic nanoemulsions, as well as from among cationic organic or inorganic particles and nanocapsules, and to the use of compositions comprising the association of at least one dsRNA and at least one cationic particle on skin models.
机译:本发明涉及通过阳离子颗粒对双链RNA寡核苷酸的载体化,所述阳离子颗粒选自表面活性剂胶束,嵌段或非嵌段聚合物胶束,阳离子脂质体和脂质体,阳离子油质体和阳离子纳米乳剂,以及选自阳离子有机或无机颗粒和纳米胶囊,以及在皮肤模型上包含至少一种dsRNA和至少一种阳离子颗粒的组合物的用途。

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