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Uses of an immunomodulatory protein (GMI) from Ganoderma microsporum

机译：灵芝小孢子中的免疫调节蛋白（GMI）的用途

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摘要

The invention provides a method for inhibiting EGF receptor activity comprising contacting an EGF receptor with an immunomodulatory protein (GMI) from Ganoderma microsporum, or a recombinant thereof. Also provided is a method for treating invasion and metastasis of cancer cells, comprising administering an effective amount of an immunomodulatory protein (GMI) from Ganoderma microsporum, or a recombinant thereof, to a subject in need of such treatment. 展开▼

机译：本发明提供了一种抑制EGF受体活性的方法，该方法包括使EGF受体与来自灵芝微孢子或其重组体的免疫调节蛋白（GMI）接触。还提供了一种用于治疗癌细胞的侵袭和转移的方法，包括向需要这种治疗的对象施用有效量的灵芝微孢子的免疫调节蛋白（GMI）或其重组体。。 展开▼

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公开/公告号US9018171B2

专利类型

公开/公告日2015-04-28

原文格式PDF

申请/专利权人 MYCOMAGIC BIOTECHNOLOGY CO. LTD.;
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申请/专利号US201314080400

发明设计人 JIUNN-LIANG KO;
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申请日2013-11-14

分类号A61K38;A61P35/04;A61K33/24;A61K38/16;C07K14/37;A61K45/06;A61K38/08;A61K31/337;A61K31/517;A61K31/5377;A61K31/704;A61K31/282;A61K31/475;

国家 US

入库时间 2022-08-21 15:18:07

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5. GMI, an Immunomodulatory Protein from Ganoderma microsporum, Potentiates Cisplatin-Induced Apoptosis via Autophagy in Lung Cancer Cells [J] . Hsin I-Lun, Ou Chu-Chyn, Wu Ming-Fang, Molecular pharmaceutics . 2015,第5期

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7. Proteome Characterization of Ganoderma Applanatum Crude Cytoplasmic Extracts from Mycelium and Spores and Identification of Shared Allergenic Proteins [D] . Martínez Zapata, Isabelita. 2018

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