Dual variable Domain immunoglobulins against vascular endothelial growth factor (VEGF) and the ligand involved in cell to Cell signaling through the receptor Notch (Dll4)

摘要

In the present report multivalent binding proteins and Methods of multi species, binding proteins, and their use in the diagnosis, Monitoring, inhibition, Prevention and / or treatment of cancer, Tumors, and / or other angiogenesis dependent diseases that character Izan by Aberrant expression or activity of Dll4 and / or VEGF.