Process for obtaining a fibrinolytic enzyme from the microalga Chlorella vulgaris

摘要

Process for obtaining a fibrinolytic enzyme from the microalga Chlorella vulgaris. Thrombosis and a disease characterized by the appearance of a blood clot, the thrombus in a blood vessel system, which determines the partial or total obstruction and prevents the local circulation. It is estimated that there are 50 cases of thrombosis every 100, 000 inhabitants.The treatment of thrombosis is done in a hospital environment, with the application of anticoagulants intravenously at high doses, to reduce blood viscosity, dissolve the clot, prevent the occurrence of pulmonary embolism and to avoid the formation of a new thrombus. The commercial thrombolytic agents are expensive and have the main disadvantage ocorru00eaencia of internal bleeding.This occurs, therefore, do not have a specific action in the clot, but general in blood system. In this sense, it is important not only to reduce the cost of production of enzymes that act on fibrinolu00edticas clots, but also develop a local application of enzyme therapy.The present invention relates the process of obtaining an enzyme with activity fibrinolu00edtu00edca and fibrinogenolu00edtica for pharmacological use using the micro organism fotossintetizante, Chlorella vulgaris.