PARTICULATES OF (4,6-BIS (DIMETHYLAMINO) -2- (4- (4- (TRIFLUOROMETIL) BENZAMIDE) -BENZIL) PYRIMINDIN-5-IL} ACETIC, METHODS FOR TREATMENT, PREVENTION OR IMPROVEMENT OR MORE SYMPTOMS OF A CRTH2-MEDIATED DISEASE, EOSINOPHILIA-RELATED DISEASE, A BASOPHYL-RELATED DISEASE, AND A PROCESS FOR THE PREPARATION OF PARTICULATES.

摘要

Provided herein are particulates of {4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl}acetic acid in amorphous or crystalline forms, processes for their preparation, pharmaceutical compositions comprising them, and methods of their use for treating, preventing, or ameliorating one or more symptoms of a CRTH2-mediated disorder or disease.