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An isolated antibody that selectively binds to beta-amyloid peptide, a pharmaceutical composition comprising said antibody, nucleic acid sequence, vector and host cell
An isolated antibody that selectively binds to beta-amyloid peptide, a pharmaceutical composition comprising said antibody, nucleic acid sequence, vector and host cell
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机译:选择性结合β-淀粉样肽的分离的抗体,包含所述抗体,核酸序列,载体和宿主细胞的药物组合物
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摘要
The invention discloses an isolated antibody that selectively binds to the C-terminal part of Abeta and is humanized or fully human. The antibody of the invention is capable of preventing oligomerization of Abeta. Furthermore, a method of diagnosis comprising the steps of: (i) Labelling an antibody; (ii) Administering an effective dose of said antibody intranasally or systemically to a subject; and (iii) Detecting the concentration and/or presence of the labelled antibody in body parts of the subject is disclosed.
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