首页> 外国专利> Methods to determine and to detect a chromosomal rearrangement, to identify a partner chromosomal rearrangement, to diagnose a disease in an individual, to detect balanced chromosomal translocation to diagnose or providing a prognosis for a lymphoma in An individual, kit, I 'IL find

Methods to determine and to detect a chromosomal rearrangement, to identify a partner chromosomal rearrangement, to diagnose a disease in an individual, to detect balanced chromosomal translocation to diagnose or providing a prognosis for a lymphoma in An individual, kit, I 'IL find

机译:确定并检测染色体重排,鉴定伴侣染色体重排,诊断个体疾病,检测平衡染色体易位以诊断或提供个体淋巴瘤预后的方法,试剂盒,我找到

摘要

The present invention provides methods for detecting and mapping chromosomal rearrangements associated with various diseases using comparative genomic hybridization. Included are methods to identify translocation partners of known genomic loci and to determine translocation breakpoints. The methods of the present invention may also be used in the prognosis, diagnosis, and determination of predisposition to diseases that involve chromosomal rearrangements such as translocations.
机译:本发明提供了使用比较基因组杂交来检测和定位与各种疾病有关的染色体重排的方法。包括鉴定已知基因组基因座的易位伴侣并确定易位断点的方法。本发明的方法还可以用于对涉及染色体重排例如易位的疾病的易感性的预后,诊断和确定。

著录项

  • 公开/公告号BRPI0820272A2

    专利类型

  • 公开/公告日2015-05-26

    原文格式PDF

  • 申请/专利权人 UNIVERSITY OF WASHINGTON;

    申请/专利号BR2008PI20272

  • 发明设计人 HARVEY A. GREISMAN;

    申请日2008-11-10

  • 分类号G01N33/48;C12P19/34;

  • 国家 BR

  • 入库时间 2022-08-21 15:16:06

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