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FERMENTATION PROCESSES FOR THE PRODUCTION OF ORGANIC ACIDS, BUTYRIC ACIDS, AND PROPIONIC ACIDS
FERMENTATION PROCESSES FOR THE PRODUCTION OF ORGANIC ACIDS, BUTYRIC ACIDS, AND PROPIONIC ACIDS
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机译:生产有机酸,布丁酸和丙酸的发酵过程
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摘要
A fermentation process for the production of organic acids is provided and includes, providing metabolically engineered mutant bacteria which have had one or both of ack and pta genes disrupted, adapting the mutant bacteria to increase their resistance to acids and to increase their growth rate by immobilizing the mutant bacteria while exposing the mutant bacteria to a fermentable substrate, and further exposing the adapted mutant bacteria to a fermentable substrate for a time sufficient to provide a final organic acid fermentation product concentration of greater than about 50 g/L.
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