Humanized antibody or binding fragment thereof, isolated nucleic acid, vector, host cell, method for producing a humanized antibody or binding fragment thereof, composition, method for treating a vwf-mediated disease or disorder in an individual, use of a humanized antibody or binding fragment thereof, method for administering the humanized antibody or binding fragment thereof, article of manufacture and kit

摘要

The present disclosure relates to humanized antibodies or binding fragments thereof specific for human von Willebrand factor (vWF), methods for their preparation and use, including methods for treating vWF mediated diseases or disorders.