A compound, pharmaceutical composition, and methods for inhibiting the formation, deposition, accumulation, or persistence of amyloid abeta or alpha-synuclein aggregates, to treat a beta-amyloid disease or synucleinopathy in a suffering mammal, to improve performance. in a mammal suffering from a synucleinopathy, and to halt the progression of motor deficits in a mammal suffering from parkinson's disease

摘要

Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of -amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.