Crystalline form c dipropilcarbamoilmetilo succinate Ester acid 3 - (3 - 2 - (e) - 3.5 - diamino - 6 - Chloro - carbonilimino pyrazine - 2 - - - - 1,3,8 triaza spiro 4.5 Dean - 8 - carbonyl} - bencenosulfonilamino) - propionic acid; Pharmaceutical Composition and Inhalation Device he understands; and its use for the Treatment of respiratory diseases such as COPD and Asthma.

摘要

This invention relates to a new crystalline form of the succinate salt of the epithelial sodium channel (ENaC) blocker 3-(3-{2-[(E)-3,5-Diamino-6-chloro-pyrazine-2-carbonylimino]-1,3,8-triaza-spiro[4.5]decane-8-carbonyl}-benzenesulfonylamino)-propionic acid dipropylcarbamoylmethyl ester, pharmaceutical compositions comprising said crystalline form, uses of said crystalline form and pharmaceutical compositions, and methods for preparing said crystalline form.