Substituted Heterocyclic compounds with amide; Pharmaceutical composition, useful in the treatment of inflammatory or Autoimmune Disease.

摘要

Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.