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PHARMACEUTICAL COMPOSITIONS ABLE to induce apoptosis in tumor cells, WHICH MAY BE USED FOR DIAGNOSIS AND TREATMENT OF CHRONIC lymphocytic B-CELL LEUKEMIA
PHARMACEUTICAL COMPOSITIONS ABLE to induce apoptosis in tumor cells, WHICH MAY BE USED FOR DIAGNOSIS AND TREATMENT OF CHRONIC lymphocytic B-CELL LEUKEMIA
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机译:能够诱导肿瘤细胞凋亡的药物组合物,可用于诊断和治疗慢性淋巴细胞B细胞白血病
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摘要
The present invention is related to the branch of immunology and particularly with the generation of pharmaceutical compositions comprising a humanized monoclonal antibody recognizing the leukocyte differentiation antigen CD6. Accordingly with that statement, the purpose of this invention is to provide pharmaceutical compositions comprising a humanized anti-CD6 monoclonal antibody for the diagnosis and treatment of Lymphoproliferative Syndromes and particularly the B-Cell Chronic Lymphocytic Leukemia. The essence of the invention consist in the application of a humanized Monoclonal Antibody that recognizes the CD6 antigen, the generation of pharmaceutical compositions comprising that antibody being able to induce apoptosis of malignant cells from B-Cell Chronic Lymphocytic Leukemia patients, reaching a clinical and a histological antitumor efficacy. The field of application of the present invention extends to the Oncology.
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