method of forecasting the risk of early development of professional u0430u043bu043bu0435u0440u0433u043eu0434u0435u0440u043cu0430u0442u043eu0437u043eu0432 with effects of chromium, nickel and cobalt

摘要

the invention relates to medicine and can be used to predict the risk of early development of professional u0430u043bu043bu0435u0440u0433u043eu0434u0435u0440u043cu0430u0442u043eu0437u043eu0432 under the impact of chromium , nickel and cobalt.the present invention is to predict the risk of the development of professional u0430u043bu043bu0435u0440u0433u043eu0434u0435u0440u043cu0430u0442u043eu0437u043eu0432 within 3 years from the beginning of continuous work with chromium omnickel and cobalt - factors u0441u0435u043du0441u0438u0431u0438u043bu0438u0437u0438u0440u0443u044eu0449u0435u0433u043e action and process of preliminary and periodic medical examinations of workers if joining in harmful and / or dangerous working conditions for short (short) period of time.this objective is achieved in that the method predicting the early development of occupational allergic dermatoses, with effects of chromium, nickel and kobe u043bu044cu0442u0430, comprising a venous blood, the genetic material a with an r.l.f.t.... with special u043fu0440u0430u0439u043cu0435u0440u0430u043cu0438,the definition of u043du0443u043au043bu0435u043eu0442u0438u0434u043du043eu0439 sequence further carry out u0430u043cu043fu043bu0438u0444u0438u043au0430u0446u0438u044e consistency in u043fu0440u043eu043cu043eu0442u043eu0440u043du043eu0439 area il - 10 gene in u043fu043eu043bu0438u043cu043eu0440u0444u043du043eu043c position - 1082, determine the sequence and on the basis u043du0443u043au043bu0435u043eu0442u0438u0434u043du0443u044e determine u043fu043eu043bu0438u043cu043eu0440u0444u043du044bu0439 version of il - 10 gene.upon detection of u0433u043eu043cu043eu0437u0438u0433u043eu0442u043du043eu0433u043e variant gene il - 10 g 1082A - aa, respectively, an early development of occupational allergic dermatoses in u0432u043eu0437u0434u0435u0439 a chromium, nickel and cobalt in the first 3 years of the start of continuous contact with chrome, nickel and cobalt - factors u0441u0435u043du0441u0438u0431u0438u043bu0438u0437u0438u0440u0443u044eu0449 his actionsin the presence of a u0433u0435u0442u0435u0440u043eu0437u0438u0433u043eu0442u043du043eu0433u043e variant gene il - 10 g 1082A ga or u0433u043eu043cu043eu0437u0438u0433u043eu0442u043du043eu0433u043e variant gene il - 10 g 1082A gg predicting the possibility of the development of allergic dermatoses in 3 years or more of work in contact with chrome, nickel and cobalt - factors u0441u0435u043du0441u0438u0431u0438u043bu0438u0437u0438u0440u0443u044eu0449u0435u0433u043e actionsallows to predict the early development of occupational allergic dermatoses during 3 years from the beginning of professional and continuing contact with the lame cobalt, nickel) - factors u0441u0435u043du0441u0438u0431u0438u043bu0438u0437u0438u0440u0443u044eu0449u0435u0433u043e action short (short) period of time.the proposed method can be used in the conduct of examinations or periodic medical examinations of workers in hazardous and / or if hazardous conditions for short (short) period of time.